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tissue_organ_import: 
Ovary: congestion, hemorrhage, involution.
Morphologic diagnosis: 
Ovary: Moderate multifocal follicular and intrafollicular hemorrhage and congestion. Ovary: Follicular atresia.
Clinical description: 
This image was taken 2 days post experimental inoculation with highly pathogenic avian influenza. The follicles on this ovary are congested and some areas have hemorrhages. Some follicles are undergoing involution and degeneration and the ovary is inactive. These findings typically correlate with a precipitous drop in egg production among infected breeders and layers. There is also some yellow proteinaceous material on the periphery of the ovary that is consistent with an unrelated chronic egg yolk peritonitis.
Pathologic description: 
The blood vessels over the ova are prominent and congested and, in some follicles, there are large, poorly demarcated red foci. The intrafollicular tissue is dark red. There are no mature ova on the ovary. Some of the follicles are becoming paler and slightly flaccid (atresia). Depending on the timing of the lay cycle, the lack of mature follicles and increased atresia can indicate disease.
Record number: 
20750
Case number: 
5005
Age: 
70 weeks
Breed: 
White Leghorn SPF
Clinical form: 
Acute
Infection type: 
Experimental
History: 
The photograph was taken 2 days post inoculation. The bird was experimentally inoculated with highly pathogenic avian influenza virus on 3/2/08 at Plum Island Animal Disease Center. The inoculation was performed in the caudal thoracic air sac with strain A/CK/PA/469/3-84/H5N2, using 0.25ml.
Zootechnical purpose: 
Egg layers- white egg
Housing/mgmnt type: 
Select One
Priority: 
1
Rights: 
© Cornell University
Etiology: 
Tissues and organs: 
Asset type: 
Image: