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Clinical Signs: 
Edema, hemorrhage, congestion (comb)
Morphologic diagnosis: 
Comb: Moderate diffuse edema with multifocal acute hemorrhage and congestion
Clinical description: 
This image was taken 2 days post experimental inoculation with highly pathogenic avian influenza. In this detailed view of the comb, edema and small hemorrhages can be seen. These lesions form as microthrombi develop within the dermal vessels of the nonfeathered skin. Thrombi lead to vasculitis, perivascular edema,subcutaneous edema, and finally necrosis of the capillary endothelium. The degree of edema, hemorrhages, and necrosis present will depend on the stage of this process.
Pathologic description: 
The subcutaneous tissues of the comb are slightly swollen and reddened. The comb is stippled by numerous, small, often coalescing faint red foci.
Record number: 
20542
Case number: 
5041
Age: 
6 weeks
Breed: 
White Leghorn SPF
Clinical form: 
Acute
Infection type: 
Experimental
History: 
The photograph was taken 2 days post inoculation. The bird was experimentally inoculated with highly pathogenic avian influenza virus on 3/2/08 at Plum Island Animal Disease Center. The inoculation was performed in the caudal thoracic air sac with strain A/CK/PA/469/3-84/H5N2, using 0.25ml.
Zootechnical purpose: 
Egg layers- white egg
Housing/mgmnt type: 
Select One
Priority: 
1
Rights: 
© Cornell University
Etiology: 
Tissues and organs: 
Asset type: 
Image: